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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CFO | SASSINE ANDY | Aug 15, 2025 | Buy | $20.5K | 1,238 |
| Chief Scientific Officer & COO | Chivukula Pad | Oct 15, 2024 | Sell | $249.12K | 12,000 |
| CFO | SASSINE ANDY | Jun 12, 2024 | Sell | $1.6M | 50,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Jun 5, 2024 | Sell | $5.13K | 114 |
| Chief Scientific Officer & COO | Chivukula Pad | Jun 3, 2024 | Sell | $1.04M | 26,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Mar 25, 2024 | Sell | $610.57K | 17,435 |
| Chief Scientific Officer & COO | Chivukula Pad | Mar 19, 2024 | Sell | $299.84K | 8,565 |
| Chief Scientific Officer & COO | Chivukula Pad | Nov 1, 2023 | Sell | $93.6K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Oct 2, 2023 | Sell | $128.06K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Sep 1, 2023 | Sell | $157.26K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Aug 1, 2023 | Sell | $174.55K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Jul 14, 2023 | Sell | $875.25K | 25,000 |
| See Remarks | Kummerfeld Keith C | Jul 14, 2023 | Sell | $243.88K | 6,968 |
| Chief Scientific Officer & COO | Chivukula Pad | Jul 3, 2023 | Sell | $143.75K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Jun 1, 2023 | Sell | $135.8K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | May 11, 2023 | Sell | $239.65K | 7,925 |
| Chief Scientific Officer & COO | Chivukula Pad | May 10, 2023 | Sell | $512.25K | 17,075 |
| Chief Scientific Officer & COO | Chivukula Pad | May 1, 2023 | Sell | $129.65K | 5,000 |
| See Remarks | Kummerfeld Keith C | Apr 18, 2023 | Sell | $196.36K | 6,968 |
| Chief Scientific Officer & COO | Chivukula Pad | Apr 3, 2023 | Sell | $126.9K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Mar 6, 2023 | Sell | $80.35K | 5,000 |
| Director | Marquet Magda | Dec 15, 2022 | Buy | $40K | 2,222 |
| CEO | Payne Joseph E | Nov 23, 2022 | Buy | $82.55K | 5,000 |
| Chief Scientific Officer & COO | Chivukula Pad | Jan 4, 2022 | Sell | $324K | 8,100 |
| Chief Scientific Officer & COO | Chivukula Pad | Dec 16, 2021 | Sell | $145.33K | 3,633 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
