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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| See Remarks | Gibney Anthony S | Jun 16, 2026 | Sell | $82.33K | 12,824 |
| 10% Owner | Matrix Capital Management Company, LP | May 7, 2026 | Sell | $39.04M | 6,922,870 |
| See Remarks | Kilroy Conor | Apr 16, 2026 | Sell | $82.4K | 11,738 |
| Director | de los Pinos Elisabet | Feb 17, 2026 | Sell | $241.1K | 47,648 |
| Chief Medical Officer | Hopkins Janet Jill | Feb 17, 2026 | Sell | $103.23K | 20,401 |
| Senior Vice President, Finance | Elazzouzi Amy | Feb 17, 2026 | Sell | $43.26K | 8,549 |
| Chief Technology Officer | Plavsic Mark | Feb 17, 2026 | Sell | $80.24K | 15,890 |
| See Remarks | Kilroy Conor | Feb 17, 2026 | Sell | $61K | 12,079 |
| Senior Vice President, Finance | Elazzouzi Amy | Jan 20, 2026 | Sell | $7.68K | 1,581 |
| Director | de los Pinos Elisabet | Jan 20, 2026 | Sell | $82.27K | 16,928 |
| Chief Medical Officer | Hopkins Janet Jill | Nov 17, 2025 | Sell | $92.73K | 17,109 |
| Senior Vice President, Finance | Elazzouzi Amy | Oct 29, 2025 | Sell | $5.69K | 896 |
| Director | de los Pinos Elisabet | Oct 29, 2025 | Sell | $57.46K | 9,049 |
| Chief Technology Officer | Plavsic Mark | Oct 16, 2025 | Sell | $77.27K | 12,169 |
| Senior Vice President, Finance | Elazzouzi Amy | Aug 18, 2025 | Sell | $51.74K | 7,722 |
| See Remarks | Gibney Anthony S | May 16, 2025 | Buy | $245K | 50,000 |
| Director | Johnson David Michael | May 16, 2025 | Buy | $98K | 20,000 |
| See Remarks | Gibney Anthony S | May 16, 2025 | Sell | $7.82K | 1,519 |
| Director | Johnson David Michael | May 16, 2025 | Buy | - | 5,000 |
| See Remarks | Gibney Anthony S | May 16, 2025 | Buy | - | 12,500 |
| Senior Vice President, Finance | Elazzouzi Amy | Apr 16, 2025 | Sell | $4.92K | 897 |
| See Remarks | Kilroy Conor | Apr 16, 2025 | Sell | $39.32K | 7,162 |
| Chief Technology Officer | Plavsic Mark | Feb 18, 2025 | Sell | $16.67K | 2,151 |
| Director | de los Pinos Elisabet | Feb 18, 2025 | Sell | $156.8K | 20,221 |
| Senior Vice President, Finance | Elazzouzi Amy | Feb 18, 2025 | Sell | $10.88K | 1,404 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.