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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Medical Officer | Simon Amy | Jul 27, 2026 | Sell | $429.04K | 16,667 |
| Chief Medical Officer | Simon Amy | Jun 30, 2026 | Sell | $12.95K | 373 |
| CEO | Evans John M. | Jun 30, 2026 | Sell | $791.48K | 23,100 |
| CEO | Evans John M. | Jun 30, 2026 | Sell | $66.2K | 1,900 |
| CEO | Evans John M. | Jun 29, 2026 | Sell | $471.53K | 13,421 |
| CEO | Evans John M. | Jun 29, 2026 | Sell | $415.82K | 11,579 |
| 10% Owner | FMR LLC | Jun 26, 2026 | Sell | $8.87M | 251,488 |
| 10% Owner | FMR LLC | Jun 25, 2026 | Sell | $1.17M | 33,372 |
| President | Ciaramella Giuseppe | Apr 1, 2026 | Sell | $290.29K | 11,810 |
| Chief Legal Officer | Bellon Christine | Apr 1, 2026 | Sell | $146.4K | 5,956 |
| Chief Medical Officer | Simon Amy | Apr 1, 2026 | Sell | $164.69K | 6,700 |
| SVP, Finance and Treasurer | Cavanagh Bethany J | Apr 1, 2026 | Sell | $79.69K | 3,242 |
| CEO | Evans John M. | Apr 1, 2026 | Sell | $739.32K | 30,078 |
| CEO | Evans John M. | Mar 31, 2026 | Sell | $569.09K | 25,000 |
| CEO | Evans John M. | Mar 30, 2026 | Sell | $559.23K | 25,000 |
| President | Ciaramella Giuseppe | Feb 24, 2026 | Sell | $1.12M | 35,000 |
| CEO | Evans John M. | Jan 30, 2026 | Sell | $624.67K | 22,094 |
| CEO | Evans John M. | Jan 30, 2026 | Sell | $84.27K | 2,906 |
| CEO | Evans John M. | Jan 29, 2026 | Sell | $476.8K | 16,333 |
| CEO | Evans John M. | Jan 29, 2026 | Sell | $257.78K | 8,667 |
| Chief Legal Officer | Bellon Christine | Jan 22, 2026 | Sell | $46.61K | 1,371 |
| SVP, Finance and Treasurer | Cavanagh Bethany J | Jan 22, 2026 | Sell | $216.93K | 6,198 |
| SVP, Finance and Treasurer | Cavanagh Bethany J | Jan 20, 2026 | Sell | $91.38K | 3,034 |
| Chief Legal Officer | Bellon Christine | Jan 15, 2026 | Sell | $70.98K | 2,111 |
| Chief Legal Officer | Bellon Christine | Jan 15, 2026 | Sell | $554.07K | 15,959 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.