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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | Erdtmann Rainer M | Dec 11, 2025 | Buy | $43K | 30,000 |
| CEO | Hitchcock Michael J.M. | Dec 2, 2025 | Buy | $99.18K | 100,000 |
| Director | Erdtmann Rainer M | Dec 1, 2025 | Buy | $10.5K | 10,000 |
| Director | Erdtmann Rainer M | Nov 28, 2025 | Buy | $44.05K | 40,000 |
| Director | Hitchcock Michael J.M. | Sep 30, 2024 | Buy | $100.6K | 10,000 |
| CFO | Valle Franco | Jun 11, 2024 | Buy | $55.36K | 12,509 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Jun 1, 2023 | Sell | $1.73M | 50,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | May 31, 2023 | Sell | $2.54M | 75,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | May 12, 2023 | Sell | $846K | 25,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | May 9, 2023 | Sell | $5.18M | 150,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | May 8, 2023 | Sell | $3.4M | 100,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Apr 20, 2023 | Sell | $5.82M | 200,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Mar 31, 2023 | Sell | $6.25M | 200,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Mar 31, 2023 | Sell | $6.25M | 200,000 |
| Director | Chen Bihua | Mar 30, 2023 | Buy | $12M | 400,000 |
| Director | Hitchcock Michael J.M. | Nov 14, 2022 | Buy | $39.65K | 5,000 |
| CFO | Valle Franco | Nov 11, 2022 | Buy | $31.29K | 4,100 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Aug 16, 2022 | Buy | $425.65K | 30,684 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Jul 21, 2022 | Sell | $388.52K | 34,658 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Jun 24, 2022 | Sell | $407.58K | 34,658 |
| CFO | Valle Franco | Jan 14, 2022 | Buy | $86.77K | 10,000 |
| 10% Owner | A2A Pharmaceuticals, Inc. | Sep 17, 2021 | Buy | $379.85K | 34,658 |
| Director | Stergiopoulos Sotirios | Sep 17, 2021 | Buy | $379.85K | 34,658 |
| CEO | Butler Thomas Andrew | Aug 23, 2021 | Buy | $316.87K | 24,000 |
| President | Erdtmann Rainer M | Aug 23, 2021 | Buy | $316.87K | 24,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.