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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | De Vre Raymond | Jun 11, 2026 | Sell | $6.17K | 2,605 |
| Chief Scientific Officer | Lutz Stefan | Feb 24, 2026 | Sell | $6.64K | 5,862 |
| CEO | MOORE ALISON | Feb 6, 2026 | Sell | $5K | 3,826 |
| Chief Scientific Officer | Lutz Stefan | Feb 6, 2026 | Sell | $3.26K | 2,492 |
| See Remarks | Erbez Georgia | Feb 6, 2026 | Sell | $5K | 3,826 |
| CSO | Lutz Stefan | Jan 7, 2026 | Sell | $7.95K | 4,685 |
| 10% Owner | Opaleye Management Inc. | Dec 1, 2025 | Sell | $408.54K | 245,000 |
| 10% Owner | Opaleye Management Inc. | Dec 1, 2025 | Sell | $14.23K | 8,533 |
| 10% Owner | Opaleye Management Inc. | Nov 28, 2025 | Sell | $183.75K | 105,000 |
| 10% Owner | Opaleye Management Inc. | Nov 28, 2025 | Sell | $4.36K | 2,490 |
| 10% Owner | Opaleye Management Inc. | Nov 26, 2025 | Sell | $258.27K | 148,318 |
| 10% Owner | Opaleye Management Inc. | Nov 26, 2025 | Sell | $8.71K | 5,000 |
| Director | WOLF DENNIS P | Nov 21, 2025 | Sell | $13.99K | 8,952 |
| 10% Owner | Opaleye Management Inc. | Nov 12, 2025 | Sell | $1.72M | 890,000 |
| 10% Owner | Opaleye Management Inc. | Nov 12, 2025 | Sell | $53.19K | 27,459 |
| 10% Owner | Opaleye Management Inc. | Nov 12, 2025 | Sell | $323.73K | 165,000 |
| Director | De Vre Raymond | Nov 11, 2025 | Sell | $2.46K | 1,413 |
| 10% Owner | Opaleye Management Inc. | Nov 11, 2025 | Sell | $962.68K | 535,000 |
| 10% Owner | Opaleye Management Inc. | Nov 11, 2025 | Sell | $23.77K | 13,211 |
| 10% Owner | Opaleye Management Inc. | Nov 10, 2025 | Sell | $355.61K | 205,000 |
| 10% Owner | Opaleye Management Inc. | Nov 10, 2025 | Sell | $5.76K | 3,318 |
| 10% Owner | Opaleye Management Inc. | Nov 7, 2025 | Sell | $503.41K | 296,682 |
| 10% Owner | Opaleye Management Inc. | Nov 7, 2025 | Sell | $16.97K | 10,000 |
| CFO | Erbez Georgia | Oct 13, 2025 | Sell | $15.63K | 6,239 |
| Chief Technical Officer | MOORE ALISON | Oct 13, 2025 | Sell | $15.63K | 6,239 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
