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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Insider | BAKER BROS. ADVISORS LP | Jul 14, 2026 | Sell | $26.79M | 261,368 |
| Insider | BAKER BROS. ADVISORS LP | Jul 14, 2026 | Sell | $290.96M | 2,838,632 |
| Director | Dalvey David | May 4, 2026 | Sell | $3.52M | 25,000 |
| Director | Buller Richard E | May 4, 2026 | Sell | $176.59K | 1,289 |
| Director | Buller Richard E | May 4, 2026 | Sell | $76.45K | 550 |
| Director | Buller Richard E | May 4, 2026 | Sell | $233.1K | 1,670 |
| Director | Buller Richard E | May 4, 2026 | Sell | $324.5K | 2,301 |
| Director | Buller Richard E | May 4, 2026 | Sell | $401.25K | 2,825 |
| Director | Buller Richard E | May 4, 2026 | Sell | $52.28K | 365 |
| Director | Buller Richard E | Mar 31, 2026 | Sell | $256K | 2,325 |
| Director | Buller Richard E | Mar 31, 2026 | Sell | $74.81K | 675 |
| Director | Dalvey David | Jan 27, 2026 | Sell | $2.4M | 20,000 |
| Director | Buller Richard E | Dec 5, 2025 | Sell | $156.96K | 1,490 |
| Director | Buller Richard E | Dec 5, 2025 | Sell | $160.11K | 1,510 |
| Director | Buller Richard E | Dec 1, 2025 | Sell | $107.95K | 1,100 |
| Director | Dalvey David | Nov 21, 2025 | Sell | $1.5M | 15,000 |
| Director | Buller Richard E | Nov 20, 2025 | Sell | $377.25K | 3,900 |
| 10% Owner | BAKER BROS. ADVISORS LP | Sep 8, 2025 | Buy | $785.73K | 13,976 |
| 10% Owner | BAKER BROS. ADVISORS LP | Sep 8, 2025 | Buy | $8.52M | 151,524 |
| 10% Owner | BAKER BROS. ADVISORS LP | Sep 8, 2025 | Buy | $22.51K | 388 |
| 10% Owner | BAKER BROS. ADVISORS LP | Sep 8, 2025 | Buy | $244.4K | 4,212 |
| Director | Dalvey David | Jul 28, 2025 | Sell | $139.17K | 3,137 |
| Director | Dalvey David | Jul 28, 2025 | Sell | $188.34K | 4,163 |
| Director | Dalvey David | Jul 28, 2025 | Sell | $93.25K | 2,025 |
| Director | Dalvey David | Jul 28, 2025 | Sell | $2.47M | 57,044 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
