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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Medical Officer | Chin Peter Scott | Sep 4, 2026 | Sell | $36.87K | 1,654 |
| Director | Thornberry Nancy | Sep 2, 2026 | Sell | $247.33K | 10,824 |
| Director | Thornberry Nancy | Sep 2, 2026 | Sell | $14.6K | 615 |
| COFO and Secretary | Schuth Alexander O. | Sep 1, 2026 | Sell | $64.88K | 2,768 |
| COFO and Secretary | Schuth Alexander O. | Aug 11, 2026 | Sell | $71.62K | 2,857 |
| CEO | Watts Ryan J. | Jan 6, 2026 | Sell | $580.77K | 35,198 |
| COFO and Secretary | Schuth Alexander O. | Jan 6, 2026 | Sell | $284.1K | 17,218 |
| Director | BAKER BROS. ADVISORS LP | Dec 11, 2025 | Buy | $3.33M | 190,523 |
| Director | BAKER BROS. ADVISORS LP | Dec 11, 2025 | Buy | $36.64M | 2,095,191 |
| Chief Medical Officer | Ho Carole | Aug 13, 2025 | Sell | $11.8K | 806 |
| COFO and Secretary | Schuth Alexander O. | Aug 12, 2025 | Sell | $39.88K | 2,937 |
| Chief Medical Officer | Ho Carole | Aug 12, 2025 | Sell | $39.88K | 2,937 |
| CEO | Watts Ryan J. | Jul 9, 2025 | Sell | $7.43M | 495,282 |
| Director | Krognes Steve E. | Jan 7, 2025 | Sell | $69.48K | 3,339 |
| COFO and Secretary | Schuth Alexander O. | Jan 7, 2025 | Sell | $60.49K | 2,907 |
| CEO | Watts Ryan J. | Jan 7, 2025 | Sell | $159.2K | 7,650 |
| Chief Medical Officer | Ho Carole | Jan 7, 2025 | Sell | $60.49K | 2,907 |
| CEO | Watts Ryan J. | Jan 6, 2025 | Sell | $591.76K | 29,266 |
| COFO and Secretary | Schuth Alexander O. | Jan 6, 2025 | Sell | $247.8K | 12,255 |
| Chief Medical Officer | Ho Carole | Jan 6, 2025 | Sell | $247.8K | 12,255 |
| Director | SATO VICKI L | Jan 2, 2025 | Sell | $64.4K | 3,080 |
| Director | Krognes Steve E. | Dec 31, 2024 | Sell | $607.5K | 30,000 |
| Director | Schenkein David P | Nov 11, 2024 | Sell | $870.57K | 27,129 |
| Director | Schenkein David P | Nov 11, 2024 | Sell | $1.06M | 32,312 |
| Director | SATO VICKI L | Nov 7, 2024 | Sell | $30.6K | 1,020 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
