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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| 10% Owner | BVF PARTNERS L P/IL | Oct 29, 2024 | Buy | $8.08M | 2,213,816 |
| 10% Owner | BVF PARTNERS L P/IL | Oct 29, 2024 | Buy | $7.66M | 2,100,244 |
| 10% Owner | BVF PARTNERS L P/IL | Oct 29, 2024 | Buy | $1.61M | 440,489 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 1,031,385 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 821,121 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 75,431 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 3,173,135 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 2,526,238 |
| 10% Owner | BVF PARTNERS L P/IL | May 9, 2024 | Buy | - | 232,068 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 1,055,445 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 837,146 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 86,341 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 2,028,645 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 1,609,063 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 165,950 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 3,084,090 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 2,446,209 |
| 10% Owner | BVF PARTNERS L P/IL | May 5, 2023 | Buy | - | 252,291 |
| President | Perrin Steven | Nov 23, 2022 | Buy | $2.6K | 1,000 |
| CEO | Gros David-Alexandre C | Dec 20, 2021 | Buy | $8.96K | 2,000 |
| CEO | Gros David-Alexandre C | Aug 17, 2021 | Buy | $24.84K | 4,000 |
| CFO | Little Paul Sean | Jun 11, 2021 | Buy | $88.7K | 10,000 |
| CEO | Gros David-Alexandre C | Jun 9, 2021 | Buy | $24.03K | 3,000 |
| 10% Owner | OrbiMed Israel GP Ltd. | Dec 2, 2020 | Sell | $2.23M | 103,200 |
| 10% Owner | Logos Global Management LP | Oct 30, 2020 | Buy | $120.16K | 5,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
