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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CFO | Geffken Daniel E. | Nov 29, 2021 | Buy | $36K | 50,000 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | May 13, 2021 | Buy | $1.73M | 1,280,624 |
| Director | Kariv Tomer | May 13, 2021 | Buy | $1.73M | 1,280,624 |
| Director | PAREKH RAJESH B | May 13, 2021 | Buy | $114.45K | 84,776 |
| Director | Nussbaum Ran | May 13, 2021 | Buy | $1.73M | 1,280,624 |
| Director | Kariv Tomer | May 13, 2021 | Buy | $3.55M | 2,630,487 |
| Director | PAREKH RAJESH B | May 13, 2021 | Buy | $3.22M | 2,381,890 |
| Director | Nussbaum Ran | May 13, 2021 | Buy | $3.55M | 2,630,487 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | May 13, 2021 | Buy | $3.55M | 2,630,487 |
| Director | Kariv Tomer | May 13, 2021 | Buy | $1.92M | 1,422,222 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | May 13, 2021 | Buy | $1.92M | 1,422,222 |
| Director | Nussbaum Ran | May 13, 2021 | Buy | $1.92M | 1,422,222 |
| Director | Kariv Tomer | May 13, 2021 | Buy | $800K | 592,592 |
| Director | Nussbaum Ran | May 13, 2021 | Buy | $800K | 592,592 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | May 13, 2021 | Buy | $800K | 592,592 |
| Director | Kariv Tomer | Jun 24, 2019 | Buy | $380.35K | 42,261 |
| Director | Nussbaum Ran | Jun 24, 2019 | Buy | $380.35K | 42,261 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Jun 24, 2019 | Buy | $380.35K | 42,261 |
| Director | Kariv Tomer | Jun 24, 2019 | Buy | $781.25K | 86,806 |
| Director | Nussbaum Ran | Jun 24, 2019 | Buy | $781.25K | 86,806 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Jun 24, 2019 | Buy | $781.25K | 86,806 |
| Director | Kariv Tomer | Jun 24, 2019 | Buy | $422.4K | 46,933 |
| Director | Nussbaum Ran | Jun 24, 2019 | Buy | $422.4K | 46,933 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Jun 24, 2019 | Buy | $422.4K | 46,933 |
| Director | Kariv Tomer | Jun 24, 2019 | Buy | $216K | 24,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.