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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CFO | Hohl Benjamin | Aug 17, 2026 | Sell | $270.17K | 4,630 |
| CFO | Hohl Benjamin | Aug 17, 2026 | Sell | $82.38K | 1,388 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Aug 17, 2026 | Sell | $227.65K | 3,900 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Aug 17, 2026 | Sell | $65.28K | 1,100 |
| Director | Derynck Mika K | Aug 4, 2026 | Sell | $9.56M | 158,795 |
| CFO | Hohl Benjamin | Jul 17, 2026 | Sell | $16.19K | 324 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jul 17, 2026 | Sell | $11.56K | 231 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jul 17, 2026 | Sell | $23.66K | 459 |
| CFO | Hohl Benjamin | Jul 17, 2026 | Sell | $19K | 369 |
| CFO | Hohl Benjamin | Jul 17, 2026 | Sell | $134.14K | 2,564 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jul 17, 2026 | Sell | $108.08K | 2,063 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jul 17, 2026 | Sell | $116.67K | 2,184 |
| CFO | Hohl Benjamin | Jul 17, 2026 | Sell | $140.82K | 2,638 |
| CFO | Hohl Benjamin | Jul 17, 2026 | Sell | $6.63K | 123 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jul 17, 2026 | Sell | $3.4K | 63 |
| Director | Kunkel Lori Anne | Jul 6, 2026 | Sell | $205.48K | 4,111 |
| Director | Kunkel Lori Anne | Jul 6, 2026 | Sell | $299.42K | 5,889 |
| 10% Owner | ORBIMED ADVISORS LLC | Jun 22, 2026 | Sell | $1.13M | 24,846 |
| 10% Owner | ORBIMED ADVISORS LLC | Jun 22, 2026 | Sell | $66.47K | 1,477 |
| 10% Owner | ORBIMED ADVISORS LLC | Jun 22, 2026 | Sell | $35.72M | 787,024 |
| 10% Owner | ORBIMED ADVISORS LLC | Jun 22, 2026 | Sell | $2.1M | 46,776 |
| CFO | Hohl Benjamin | Jun 17, 2026 | Sell | $59K | 1,379 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jun 17, 2026 | Sell | $54.3K | 1,268 |
| CFO | Hohl Benjamin | Jun 17, 2026 | Sell | $149.18K | 3,401 |
| CHIEF MEDICAL OFFICER | Collins Helen Louise | Jun 17, 2026 | Sell | $114.02K | 2,599 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
