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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Corp. & Bus. Dev. Ofcr | Doyle Janeen Noel | Jun 2, 2026 | Sell | $56.94K | 4,059 |
| Vice President, Accounting | Dobek Maria | May 11, 2026 | Sell | $28.88K | 2,038 |
| CEO | Campbell David Alan | Jan 2, 2026 | Sell | $110.83K | 8,072 |
| Chief Technical Officer | Winter Charles M. | Jan 2, 2026 | Sell | $32.97K | 2,401 |
| Chief Business Officer | Meyer Andrew Hollman | Jan 2, 2026 | Sell | $25.8K | 1,879 |
| Vice President, Accounting | Dobek Maria | Jan 2, 2026 | Sell | $20.07K | 1,462 |
| Chief Scientific Officer | DiRaimondo Thomas | Jan 2, 2026 | Sell | $34.39K | 2,505 |
| Chief Medical Officer | McIver Zachariah | Jan 2, 2026 | Sell | $37.26K | 2,714 |
| Chief Business Officer | Meyer Andrew Hollman | Dec 1, 2025 | Sell | $88.71K | 2,700 |
| Chief Business Officer | Meyer Andrew Hollman | Dec 1, 2025 | Sell | $21.22K | 633 |
| Chief Business Officer | Meyer Andrew Hollman | Nov 14, 2025 | Sell | $99.99K | 3,333 |
| Chief Business Officer | Meyer Andrew Hollman | Oct 28, 2025 | Sell | $500.99K | 16,665 |
| Chief Business Officer | Meyer Andrew Hollman | May 1, 2025 | Sell | $93.7K | 2,933 |
| Chief Business Officer | Meyer Andrew Hollman | May 1, 2025 | Sell | $13.04K | 400 |
| Chief Business Officer | Meyer Andrew Hollman | Apr 21, 2025 | Sell | $100.02K | 3,334 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 7, 2025 | Buy | $3.42M | 110,206 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 6, 2025 | Buy | $11.45M | 372,093 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 5, 2025 | Buy | $9.3M | 304,287 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 5, 2025 | Buy | $1.17M | 37,455 |
| Chief Business Officer | Meyer Andrew Hollman | Mar 3, 2025 | Sell | $77.58K | 2,433 |
| Chief Business Officer | Meyer Andrew Hollman | Mar 3, 2025 | Sell | $29.6K | 901 |
| Chief Business Officer | Meyer Andrew Hollman | Feb 3, 2025 | Sell | $101.74K | 2,418 |
| Chief Business Officer | Meyer Andrew Hollman | Feb 3, 2025 | Sell | $34.9K | 816 |
| Chief Business Officer | Meyer Andrew Hollman | Feb 3, 2025 | Sell | $4.36K | 100 |
| CEO | Campbell David Alan | Jan 7, 2025 | Sell | $300K | 5,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.