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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Accounting Officer | Abate Kristin | Sep 1, 2026 | Sell | $38.38 | 19 |
| EVP, Chief Development Officer | Poulton Stuart | Jul 28, 2026 | Sell | $1.34K | 189 |
| Chief Accounting Officer | Abate Kristin | May 14, 2026 | Sell | $503.5 | 53 |
| EVP, CLO&Secretary | Mano Michael | May 14, 2026 | Sell | $2.53K | 266 |
| EVP & Chief Medical Officer | Rangwala Reshma | May 14, 2026 | Sell | $3.88K | 408 |
| CEO | Paulson Richard A. | May 14, 2026 | Sell | $20.93K | 2,203 |
| EVP & Chief Commercial Officer | Cheng Sohanya Roshan | May 14, 2026 | Sell | $3.08K | 324 |
| EVP, Chief Development Officer | Poulton Stuart | May 14, 2026 | Sell | $3.83K | 403 |
| EVP & Chief Medical Officer | Rangwala Reshma | Apr 21, 2026 | Sell | $4.01K | 449 |
| EVP & Chief Commercial Officer | Cheng Sohanya Roshan | Mar 2, 2026 | Sell | $43.32K | 4,604 |
| EVP & Chief Medical Officer | Rangwala Reshma | Mar 2, 2026 | Sell | $47.67K | 5,066 |
| CEO | Paulson Richard A. | Mar 2, 2026 | Sell | $116.31K | 12,361 |
| EVP, Chief Development Officer | Poulton Stuart | Mar 2, 2026 | Sell | $48K | 5,101 |
| EVP, CLO&Secretary | Mano Michael | Mar 2, 2026 | Sell | $33.18K | 3,526 |
| Chief Accounting Officer | Abate Kristin | Mar 2, 2026 | Sell | $5.26K | 559 |
| EVP, Chief Development Officer | Poulton Stuart | Feb 17, 2026 | Sell | $3.26K | 378 |
| CFO | Macomber Lori | Feb 3, 2026 | Sell | $10.24K | 1,626 |
| Chief Accounting Officer | Abate Kristin | Jan 28, 2026 | Sell | $351.5 | 50 |
| Chief Accounting Officer | Abate Kristin | Jan 21, 2026 | Sell | $1.58K | 265 |
| Chief Accounting Officer | Abate Kristin | Oct 1, 2025 | Sell | $2.28K | 362 |
| EVP & Chief Commercial Officer | Cheng Sohanya Roshan | Sep 15, 2025 | Sell | $2.09K | 325 |
| EVP, Chief Development Officer | Poulton Stuart | Sep 15, 2025 | Sell | $2.58K | 401 |
| EVP & Chief Medical Officer | Rangwala Reshma | Sep 15, 2025 | Sell | $2.62K | 408 |
| Chief Accounting Officer | Abate Kristin | Sep 15, 2025 | Sell | $147.89 | 23 |
| SVP, General Counsel&Secretary | Mano Michael | Sep 15, 2025 | Sell | $1.5K | 234 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.