Best Investments/trading ideas for the weekJoin our free webinar on September23,2026.

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Best Investments/trading ideas for the weekJoin our free webinar on September23,2026.

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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Corp. Controller & VP, Finance | Tanini Annita | Aug 18, 2026 | Sell | $12.59K | 1,224 |
| Director | Newton Charles W. | Aug 18, 2026 | Sell | $5.68K | 551 |
| Chief Scientific Officer | Lerner Lorena Raquel | Aug 18, 2026 | Sell | $36.71K | 3,568 |
| Chief Legal Officer | Cho Esther | Aug 18, 2026 | Sell | $46.15K | 4,485 |
| Director | BIENAIME JEAN JACQUES | Aug 17, 2026 | Buy | $10.27K | 1,000 |
| Director | BIENAIME JEAN JACQUES | Jul 15, 2026 | Buy | $10.61K | 1,000 |
| Director | BIENAIME JEAN JACQUES | Jun 15, 2026 | Buy | $10.19K | 1,000 |
| Director | Newton Charles W. | Jun 11, 2026 | Sell | $5.52K | 550 |
| Director | Seth Alpna | Jun 4, 2026 | Sell | $28.14K | 2,625 |
| Director | Farzan Nima | Jun 4, 2026 | Sell | $28.17K | 2,625 |
| Director | Knowles Julius | Jun 4, 2026 | Sell | $28.17K | 2,625 |
| Director | BIENAIME JEAN JACQUES | May 15, 2026 | Buy | $10.58K | 1,000 |
| Director | BIENAIME JEAN JACQUES | Apr 15, 2026 | Buy | $11.7K | 1,000 |
| Director | BIENAIME JEAN JACQUES | Mar 9, 2026 | Buy | $22.42K | 2,000 |
| CEO | Seehra Jasbir | Feb 19, 2026 | Sell | $113.43K | 7,015 |
| Chief Science Officer | Lerner Lorena Raquel | Feb 18, 2026 | Sell | $63.32K | 3,873 |
| CFO | Regnante Keith | Feb 18, 2026 | Sell | $77.48K | 4,739 |
| SVP, General Counsel | Cho Esther | Feb 18, 2026 | Sell | $77.58K | 4,745 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Oct 15, 2025 | Sell | $40.55M | 2,284,612 |
| 10% Owner | ADAR1 Capital Management, LLC | Oct 15, 2025 | Sell | $77.94M | 4,391,237 |
| 10% Owner | ADAR1 Capital Management, LLC | Oct 15, 2025 | Sell | $4.52M | 254,669 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Oct 15, 2025 | Sell | $19.9M | 1,121,045 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Oct 15, 2025 | Sell | $21.77M | 1,226,412 |
| 10% Owner | ADAR1 Capital Management, LLC | Oct 15, 2025 | Sell | $13.19M | 743,358 |
| 10% Owner | Pontifax Management 4 G.P. (2015) Ltd. | Oct 15, 2025 | Sell | $2.76M | 155,262 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.