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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | WILSON TROY EDWARD | Aug 24, 2026 | Buy | $1.24M | 100,000 |
| Chief Commercial Officer | Powl Brian T. | Aug 21, 2026 | Sell | $51.66K | 4,345 |
| Chief Legal Officer | Bair Teresa Brophy | Aug 19, 2026 | Sell | $397.68K | 31,487 |
| CEO | WILSON TROY EDWARD | Aug 17, 2026 | Buy | $1.11M | 100,000 |
| Chief Medical Officer | Leoni Mollie | Jun 18, 2026 | Sell | $834.28K | 84,929 |
| Chief Commercial Officer | Powl Brian T. | May 21, 2026 | Sell | $110K | 10,000 |
| Chief Commercial Officer | Powl Brian T. | May 19, 2026 | Sell | $3.12K | 339 |
| Chief Operating Officer | FORD KATHLEEN | May 19, 2026 | Sell | $20.48K | 2,257 |
| Chief Legal Officer | Bair Teresa Brophy | May 18, 2026 | Sell | $21.16K | 2,256 |
| Chief Scientific Officer | Burrows Francis | Jan 27, 2026 | Sell | $11.09K | 1,311 |
| Chief Legal Officer | Bair Teresa Brophy | Jan 27, 2026 | Sell | $34.66K | 4,096 |
| Chief Operating Officer | FORD KATHLEEN | Jan 27, 2026 | Sell | $15.34K | 1,813 |
| SVP, Finance & Accounting | DOYLE THOMAS JAMES | Jan 27, 2026 | Sell | $18.83K | 2,226 |
| Chief Commercial Officer | Powl Brian T. | Jan 27, 2026 | Sell | $40.97K | 4,842 |
| Chief Medical Officer | Leoni Mollie | Jan 27, 2026 | Sell | $30.92K | 3,655 |
| Chief Legal Officer | Bair Teresa Brophy | Jan 27, 2026 | Sell | $19.76K | 2,335 |
| Chief Medical Officer | Leoni Mollie | Jan 27, 2026 | Sell | $18.89K | 2,233 |
| SVP, Finance & Accounting | DOYLE THOMAS JAMES | Jan 27, 2026 | Sell | $9.43K | 1,114 |
| Chief Commercial Officer | Powl Brian T. | Jan 27, 2026 | Sell | $13.3K | 1,572 |
| Chief Legal Officer | Bair Teresa Brophy | Jan 27, 2026 | Sell | $40.42K | 4,777 |
| Chief Medical Officer | Leoni Mollie | Jan 27, 2026 | Sell | $8.05K | 951 |
| SVP, Finance & Accounting | DOYLE THOMAS JAMES | Jan 27, 2026 | Sell | $5.88K | 695 |
| Chief Medical Officer | Leoni Mollie | Jan 27, 2026 | Sell | $11.35K | 1,341 |
| SVP, Finance & Accounting | DOYLE THOMAS JAMES | Jan 27, 2026 | Sell | $18.83K | 2,226 |
| SVP, Finance & Accounting | DOYLE THOMAS JAMES | Jan 27, 2026 | Sell | $7.45K | 881 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
