Best Investments/trading ideas for the weekJoin our free webinar on September23,2026.

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Best Investments/trading ideas for the weekJoin our free webinar on September23,2026.

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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Medical Officer | Azoulay Salomon | Aug 4, 2026 | Sell | $24.33K | 370 |
| Chief Medical Officer | Azoulay Salomon | May 8, 2026 | Sell | $2.11M | 55,000 |
| Chief Medical Officer | Azoulay Salomon | May 8, 2026 | Sell | $574.61K | 15,003 |
| CEO | Hawryluk P. Kent | May 6, 2026 | Sell | $17.93K | 607 |
| Chief Medical Officer | Azoulay Salomon | May 6, 2026 | Sell | $6.82K | 231 |
| CEO | Hawryluk P. Kent | Mar 13, 2026 | Buy | $525.66K | 18,500 |
| CEO | Hawryluk P. Kent | Oct 20, 2025 | Buy | $272.79K | 20,000 |
| Director | Hoerter Steven L. | Oct 17, 2025 | Buy | $264.98K | 20,000 |
| Director | Heron Patrick J | Sep 26, 2025 | Buy | $12M | 666,666 |
| Director | Pescovitz Ora H. | Apr 8, 2025 | Buy | $45.31K | 7,693 |
| Director | ORBIMED ADVISORS LLC | Feb 18, 2025 | Buy | $531.92K | 49,070 |
| Director | GORDON CARL L | Feb 18, 2025 | Buy | $531.92K | 49,070 |
| Director | ORBIMED ADVISORS LLC | Feb 18, 2025 | Buy | $1.02M | 94,100 |
| Director | GORDON CARL L | Feb 18, 2025 | Buy | $1.02M | 94,100 |
| Director | ORBIMED ADVISORS LLC | Feb 14, 2025 | Buy | $177.82K | 17,962 |
| Director | GORDON CARL L | Feb 14, 2025 | Buy | $177.82K | 17,962 |
| Director | ORBIMED ADVISORS LLC | Feb 14, 2025 | Buy | $290.97K | 29,540 |
| Director | GORDON CARL L | Feb 14, 2025 | Buy | $290.97K | 29,540 |
| CEO | Hawryluk P. Kent | Feb 4, 2025 | Buy | $534.5K | 50,000 |
| Director | Aynechi Tiba | Sep 16, 2024 | Buy | $12M | 750,000 |
| Director | Heron Patrick J | Sep 16, 2024 | Buy | $10M | 625,000 |
| 10% Owner | Frazier Life Sciences X, L.P. | Sep 16, 2024 | Buy | $10M | 625,000 |
| 10% Owner | Makhzoumi Mohamad | Sep 16, 2024 | Buy | $8M | 500,000 |
| 10% Owner | New Enterprise Associates 17, L.P. | Sep 16, 2024 | Buy | $8M | 500,000 |
| 10% Owner | Walker Paul Edward | Sep 16, 2024 | Buy | $8M | 500,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.