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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | HEIDEN WILLIAM K | Aug 20, 2025 | Buy | $73.76K | 49,500 |
| Director | HEIDEN WILLIAM K | Aug 19, 2025 | Buy | $76.76K | 50,500 |
| VP, Controller & Treasurer | Smith Beth Ann | Feb 15, 2025 | Sell | $1.08K | 423 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Apr 4, 2024 | Sell | $640.48K | 42,500 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Apr 4, 2024 | Sell | $2.28K | 147 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Apr 4, 2024 | Sell | $3.8K | 232 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Apr 4, 2024 | Sell | $94.93K | 5,351 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Apr 4, 2024 | Sell | $57.67K | 3,165 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Mar 6, 2024 | Sell | $421.94K | 19,625 |
| CFO | Karrels James | Mar 4, 2024 | Sell | $615K | 30,000 |
| Chief Operating Officer | Risser Eric Blasius | Mar 4, 2024 | Sell | $300K | 15,000 |
| Sr VP, Technical Ops | Spitznagel Thomas | Mar 4, 2024 | Sell | $200K | 10,000 |
| Chief Operating Officer | Risser Eric Blasius | Mar 4, 2024 | Sell | $513.5K | 26,159 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Feb 26, 2024 | Sell | $277.66K | 16,124 |
| Sr VP, Research & CSO | Bonvini Ezio | Feb 7, 2024 | Sell | $60.01K | 3,334 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Feb 5, 2024 | Sell | $897.2K | 54,376 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Feb 5, 2024 | Sell | $360.94K | 21,875 |
| Sr VP, Research & CSO | Bonvini Ezio | Feb 1, 2024 | Sell | $199.74K | 13,316 |
| Sr VP, Research & CSO | Bonvini Ezio | Jan 19, 2024 | Sell | $159.79K | 13,316 |
| Sr VP, Research & CSO | Bonvini Ezio | Dec 20, 2023 | Sell | $190.31K | 18,880 |
| 10% Owner | BIOTECH TARGET N V | Oct 2, 2023 | Buy | $669.59K | 150,000 |
| 10% Owner | BIOTECH TARGET N V | Sep 7, 2023 | Buy | $1.05M | 200,000 |
| Director | HURWITZ EDWARD | Aug 30, 2023 | Buy | $73.65K | 15,000 |
| Senior VP and General Counsel | Peters Jeffrey Stuart | Mar 10, 2023 | Sell | $32.39K | 5,372 |
| 10% Owner | BIOTECH TARGET N V | Feb 14, 2023 | Buy | $2.53M | 500,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.