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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| See Remarks | Wein Matthew | Jun 5, 2026 | Sell | $724.84 | 558 |
| Director | Irish Jian | Jun 5, 2026 | Sell | $4.85K | 3,737 |
| CFO | Wapnick Pamela | Jun 5, 2026 | Sell | $3.75K | 2,884 |
| See Remarks | Wein Matthew | Mar 5, 2026 | Sell | $771.2 | 482 |
| CFO | Wapnick Pamela | Mar 5, 2026 | Sell | $2.53K | 1,581 |
| CEO | Irish Jian | Mar 5, 2026 | Sell | $2.57K | 1,607 |
| Director | Thomas Brian C. | Dec 5, 2025 | Sell | $6.79K | 3,830 |
| See Remarks | Wein Matthew | Dec 5, 2025 | Sell | $352.61 | 199 |
| CEO | Irish Jian | Dec 5, 2025 | Sell | $2.84K | 1,602 |
| CFO | Wapnick Pamela | Dec 5, 2025 | Sell | $2.79K | 1,576 |
| See Remarks | Wein Matthew | Sep 5, 2025 | Sell | $360.19 | 199 |
| CEO | Irish Jian | Sep 5, 2025 | Sell | $2.9K | 1,602 |
| CFO | Wapnick Pamela | Sep 5, 2025 | Sell | $2.85K | 1,576 |
| Director | Thomas Brian C. | Sep 5, 2025 | Sell | $4.89K | 2,701 |
| CFO | Wapnick Pamela | Jun 6, 2025 | Sell | $2.76K | 1,576 |
| Director | Irish Jian | Jun 6, 2025 | Sell | $11.18K | 6,390 |
| Chief Medical Officer | Noonberg Sarah B. | Jun 6, 2025 | Sell | $9.17K | 5,239 |
| CEO | Thomas Brian C. | Jun 6, 2025 | Sell | $18.87K | 10,785 |
| See Remarks | Wein Matthew | Jun 6, 2025 | Sell | $348.25 | 199 |
| CFO | Wapnick Pamela | Mar 5, 2025 | Sell | $3.39K | 1,808 |
| See Remarks | Wein Matthew | Mar 5, 2025 | Sell | $1.74K | 930 |
| CFO | Wapnick Pamela | Dec 5, 2024 | Sell | $2.9K | 1,559 |
| CFO | Wapnick Pamela | Sep 5, 2024 | Sell | $18.04K | 6,265 |
| 10% Owner | Novo Holdings A/S | Feb 13, 2024 | Buy | $12M | 800,000 |
| 10% Owner | Novo Holdings A/S | Feb 9, 2024 | Buy | $1.03M | 100,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.