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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | Oliveto Joseph | Apr 16, 2026 | Sell | $82.49K | 36,500 |
| CEO | Oliveto Joseph | Jan 26, 2026 | Sell | $66.63K | 34,523 |
| Chief Commercial Officer | Muller Lorenz | Jan 26, 2026 | Sell | $21.58K | 11,180 |
| CFO | Hasija Amit | Jan 26, 2026 | Sell | $23.63K | 12,245 |
| Chief Medical Officer | Bharucha David | Jan 26, 2026 | Sell | $23.63K | 12,245 |
| Chief Operating Officer | Nelson Jeffrey Edward | Jan 26, 2026 | Sell | $23.63K | 12,245 |
| CEO | Oliveto Joseph | Jan 8, 2026 | Sell | $96.75K | 43,000 |
| CEO | Oliveto Joseph | Jan 7, 2026 | Sell | $1.13K | 500 |
| CEO | Oliveto Joseph | Dec 15, 2025 | Sell | $308.69K | 133,054 |
| Chief Commercial Officer | Muller Lorenz | Dec 15, 2025 | Sell | $124.27K | 53,566 |
| Chief Operating Officer | Nelson Jeffrey Edward | Dec 15, 2025 | Sell | $134.58K | 58,007 |
| Chief Medical Officer | Bharucha David | Dec 15, 2025 | Sell | $134.58K | 58,007 |
| CFO | Hasija Amit | Dec 15, 2025 | Sell | $134.58K | 58,007 |
| Chief Medical Officer | Bharucha David | Dec 5, 2022 | Buy | $32.83K | 7,000 |
| Chief Medical Officer | Bharucha David | Dec 1, 2022 | Buy | $14.58K | 3,000 |
| Director | Liebert Debra K. | Oct 21, 2022 | Buy | $21.04K | 4,000 |
| Director | Pasternak Richard C | Oct 20, 2022 | Buy | $52K | 10,000 |
| Director | Liebert Debra K. | Oct 20, 2022 | Buy | $52.9K | 10,000 |
| Director | Wills Robert James | Oct 19, 2022 | Buy | $73.95K | 15,000 |
| Director | TOMSICEK MICHAEL JOHN | Oct 19, 2022 | Buy | $79.8K | 15,000 |
| 10% Owner | RTW INVESTMENTS, LP | Sep 7, 2022 | Buy | $13.56M | 1,557,346 |
| 10% Owner | RTW INVESTMENTS, LP | Sep 7, 2022 | Sell | $13.56M | 1,557,346 |
| Director | TRUEX PAUL F | May 31, 2022 | Buy | $28K | 5,000 |
| 10% Owner | RTW INVESTMENTS, LP | May 21, 2021 | Buy | $4.99M | 910,746 |
| 10% Owner | RTW INVESTMENTS, LP | Oct 27, 2020 | Buy | $4.99M | 952,380 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.