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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Scientific Officer | Reich Kristian | Jul 27, 2026 | Sell | $22K | 1,100 |
| Chief Scientific Officer | Reich Kristian | Jul 22, 2026 | Sell | $48.96K | 2,448 |
| Chief Scientific Officer | Reich Kristian | Jul 21, 2026 | Sell | $1M | 50,000 |
| Chief Scientific Officer | Reich Kristian | Jul 20, 2026 | Sell | $877.93K | 43,700 |
| Chief Scientific Officer | Reich Kristian | Jul 15, 2026 | Sell | $322.26K | 16,105 |
| CEO | Santos da Silva Jorge | Jul 10, 2026 | Sell | $1.37M | 68,289 |
| CEO | Santos da Silva Jorge | Jul 9, 2026 | Sell | $679.06K | 33,936 |
| CEO | Santos da Silva Jorge | Jul 1, 2026 | Sell | $956.93K | 47,775 |
| CFO | Bodenstedt Matthias | Jun 22, 2026 | Sell | $862.2K | 39,120 |
| CFO | Bodenstedt Matthias | Jun 18, 2026 | Sell | $54.76K | 2,794 |
| CFO | Bodenstedt Matthias | Jun 17, 2026 | Sell | $296.81K | 15,082 |
| Chief Scientific Officer | Reich Kristian | Jun 17, 2026 | Sell | $971.5K | 50,000 |
| Chief Scientific Officer | Reich Kristian | Jun 16, 2026 | Sell | $935K | 50,000 |
| Chief Scientific Officer | Reich Kristian | Jun 15, 2026 | Sell | $944.5K | 50,000 |
| CFO | Bodenstedt Matthias | May 11, 2026 | Sell | $273.33K | 13,653 |
| CFO | Bodenstedt Matthias | Apr 14, 2026 | Sell | $47.45K | 2,426 |
| CEO | Santos da Silva Jorge | Apr 13, 2026 | Sell | $945.64K | 51,873 |
| CEO | Santos da Silva Jorge | Apr 10, 2026 | Sell | $1.81M | 98,127 |
| CFO | Bodenstedt Matthias | Apr 10, 2026 | Sell | $37.56K | 1,925 |
| CFO | Bodenstedt Matthias | Apr 9, 2026 | Sell | $1.63M | 85,870 |
| Director | BVF PARTNERS L P/IL | Mar 31, 2026 | Sell | $32.44M | 1,932,354 |
| Director | BVF PARTNERS L P/IL | Mar 31, 2026 | Sell | $26.35M | 1,569,116 |
| Director | BVF PARTNERS L P/IL | Mar 31, 2026 | Sell | $4.17M | 248,530 |
| CEO | Santos da Silva Jorge | Dec 9, 2025 | Sell | $1.01M | 70,000 |
| Chief Scientific Officer | Reich Kristian | Dec 9, 2025 | Sell | $1.05M | 72,908 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.