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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | HASTINGS PAUL J | Jun 18, 2026 | Sell | $4.81K | 1,776 |
| CEO | HASTINGS PAUL J | Jan 15, 2026 | Sell | $53.92K | 26,046 |
| President | Mahmood Nadir | Jan 15, 2026 | Sell | $11.69K | 5,649 |
| CEO | HASTINGS PAUL J | Jun 18, 2025 | Sell | $3.2K | 1,790 |
| Chief Technical Officer | Brandenberger Ralph | Jan 15, 2025 | Sell | $16.38K | 7,447 |
| Chief Legal Officer | Hager Alicia J. | Jan 15, 2025 | Sell | $21.08K | 9,584 |
| CEO | HASTINGS PAUL J | Jan 15, 2025 | Sell | $38.23K | 17,378 |
| See Remarks | Levin Alyssa | Jan 15, 2025 | Sell | $12.84K | 5,838 |
| See Remarks | Shook David | Jan 15, 2025 | Sell | $19K | 8,638 |
| Chief Legal Officer | Hager Alicia J. | Jul 16, 2024 | Sell | $27.17K | 3,396 |
| Chief Technical Officer | Brandenberger Ralph | Jun 18, 2024 | Sell | $1.28K | 229 |
| Chief Medical Officer | Shook David | Jun 18, 2024 | Sell | $2.55K | 456 |
| Chief Legal Officer | Hager Alicia J. | Jun 18, 2024 | Sell | $4.07K | 727 |
| CEO | HASTINGS PAUL J | Jun 18, 2024 | Sell | $9.91K | 1,770 |
| Chief Scientific Officer | Trager James | Jun 18, 2024 | Sell | $2.55K | 456 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 27, 2024 | Buy | $30M | 3,000,000 |
| Director | George Simeon | Mar 27, 2024 | Buy | $15.48M | 1,548,341 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Mar 27, 2024 | Buy | $30M | 3,000,031 |
| Director | George Simeon | Mar 27, 2024 | Buy | $4.52M | 451,659 |
| Chief Technical Officer | Brandenberger Ralph | Mar 1, 2024 | Sell | $104.67K | 8,367 |
| Chief Scientific Officer | Trager James | Feb 12, 2024 | Sell | $49.72K | 4,143 |
| CEO | HASTINGS PAUL J | Jan 16, 2024 | Sell | $84.75K | 9,697 |
| Chief Legal Officer | Hager Alicia J. | Jan 16, 2024 | Sell | $39.8K | 4,554 |
| Chief Medical Officer | Shook David | Jan 16, 2024 | Sell | $31.04K | 3,552 |
| Chief Technical Officer | Brandenberger Ralph | Jan 16, 2024 | Sell | $21.95K | 2,512 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
