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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | Saccomano Nicholas A | Jun 22, 2026 | Sell | $378.08 | 86 |
| CFO | Leverone Jason A. | Jun 22, 2026 | Sell | $1.33K | 303 |
| CFO | Leverone Jason A. | Mar 23, 2026 | Sell | $1.25K | 301 |
| CEO | Saccomano Nicholas A | Mar 23, 2026 | Sell | $357.46 | 86 |
| CFO | Leverone Jason A. | Dec 22, 2025 | Sell | $896.25 | 302 |
| CEO | Saccomano Nicholas A | Dec 22, 2025 | Sell | $258.19 | 87 |
| CEO | Saccomano Nicholas A | Sep 22, 2025 | Sell | $230.87 | 88 |
| CFO | Leverone Jason A. | Sep 22, 2025 | Sell | $794.92 | 303 |
| CFO | Leverone Jason A. | Jun 23, 2025 | Sell | $722.41 | 303 |
| CEO | Saccomano Nicholas A | Jun 23, 2025 | Sell | $209.81 | 88 |
| Insider | Cormorant Asset Management, LP | May 15, 2025 | Sell | $3.36M | 1,813,439 |
| 10% Owner | ACORN BIOVENTURES, L.P. | May 15, 2025 | Buy | $500K | 270,270 |
| 10% Owner | ACORN BIOVENTURES, L.P. | May 15, 2025 | Buy | $2.09M | 1,129,730 |
| 10% Owner | Cormorant Asset Management, LP | May 12, 2025 | Sell | $48.24K | 24,300 |
| CFO | Leverone Jason A. | Apr 7, 2025 | Sell | $4.93K | 1,844 |
| CEO | Saccomano Nicholas A | Apr 7, 2025 | Sell | $1.38K | 516 |
| CFO | Leverone Jason A. | Apr 4, 2025 | Sell | $4.25K | 1,278 |
| CEO | Saccomano Nicholas A | Apr 4, 2025 | Sell | $1.19K | 358 |
| 10% Owner | Leonard Braden Michael | Sep 25, 2024 | Buy | $102.87K | 68,746 |
| 10% Owner | Leonard Braden Michael | Sep 24, 2024 | Buy | $41.87K | 29,600 |
| 10% Owner | Leonard Braden Michael | Sep 18, 2024 | Buy | $1.13K | 806 |
| 10% Owner | Leonard Braden Michael | Sep 17, 2024 | Buy | $75.11K | 55,300 |
| 10% Owner | Leonard Braden Michael | Sep 16, 2024 | Buy | $236.87K | 172,747 |
| 10% Owner | Leonard Braden Michael | Sep 13, 2024 | Buy | $196.95K | 150,000 |
| 10% Owner | Leonard Braden Michael | Sep 12, 2024 | Buy | $50.52K | 36,176 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.