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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Operating Officer | Sandler Laura Lee | Sep 1, 2026 | Sell | $91.05K | 1,000 |
| CEO | Klein Lawrence Otto | Sep 1, 2026 | Sell | $599.56K | 6,604 |
| Chief Operating Officer | Sandler Laura Lee | Sep 1, 2026 | Sell | $368.05K | 4,000 |
| CEO | Klein Lawrence Otto | Sep 1, 2026 | Sell | $5.84M | 63,596 |
| CEO | Klein Lawrence Otto | Sep 1, 2026 | Sell | $443.69K | 4,800 |
| Chief Medical Officer | Goncalves Joana | Aug 17, 2026 | Sell | $98.69K | 900 |
| Chief Medical Officer | Goncalves Joana | Aug 17, 2026 | Sell | $33.16K | 300 |
| Chief Medical Officer | Goncalves Joana | Aug 17, 2026 | Sell | $371.89K | 3,320 |
| Chief Medical Officer | Goncalves Joana | Aug 17, 2026 | Sell | $279.15K | 2,480 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $384.96K | 3,630 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $1.12M | 10,434 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $1.59M | 14,696 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $1.11M | 10,200 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $1.01M | 9,193 |
| General Counsel | Quinlan Paul T | Aug 14, 2026 | Sell | $427.55K | 3,847 |
| Senior Vice President, Finance | Agarwal Arjun | Aug 13, 2026 | Sell | $219.81K | 2,100 |
| Senior Vice President, Finance | Agarwal Arjun | Aug 13, 2026 | Sell | $225.08K | 2,132 |
| Senior Vice President, Finance | Agarwal Arjun | Aug 13, 2026 | Sell | $135.2K | 1,268 |
| Senior Vice President, Finance | Agarwal Arjun | Aug 13, 2026 | Sell | $230.72K | 2,142 |
| Senior Vice President, Finance | Agarwal Arjun | Aug 13, 2026 | Sell | $255.76K | 2,358 |
| Chief Medical Officer | Goncalves Joana | Jul 15, 2026 | Sell | $33.75K | 400 |
| Chief Medical Officer | Goncalves Joana | Jul 15, 2026 | Sell | $214.39K | 2,497 |
| Chief Medical Officer | Goncalves Joana | Jul 15, 2026 | Sell | $329.63K | 3,803 |
| Chief Medical Officer | Goncalves Joana | Jul 15, 2026 | Sell | $26.18K | 300 |
| Senior Vice President, Finance | Agarwal Arjun | Jul 13, 2026 | Sell | $24.92K | 300 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.