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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Chief Technical Officer | Kasraian Kasra | May 21, 2026 | Sell | $1.74K | 1,233 |
| CEO | McArthur James G | Mar 4, 2026 | Sell | $32.05K | 5,144 |
| EVP, Head of R&D | STRECK PAUL | Mar 4, 2026 | Sell | $11.41K | 1,832 |
| CFO | Donnelly Noel | Mar 4, 2026 | Sell | $12.66K | 2,032 |
| CEO | McArthur James G | Mar 4, 2026 | Sell | $828.58 | 131 |
| EVP, Head of R&D | STRECK PAUL | Mar 4, 2026 | Sell | $295.54 | 47 |
| CFO | Donnelly Noel | Mar 4, 2026 | Sell | $328.9 | 52 |
| Insider | Oxford Science Enterprises plc | Sep 30, 2025 | Buy | $640K | 200,000 |
| Director | RA CAPITAL MANAGEMENT, L.P. | Sep 26, 2025 | Buy | $30M | 9,375,000 |
| EVP, Head of R&D | STRECK PAUL | May 30, 2025 | Buy | $10.39K | 8,375 |
| CEO | McArthur James G | Apr 17, 2025 | Buy | $13.55K | 10,000 |
| CEO | McArthur James G | Apr 8, 2025 | Buy | $47.72K | 41,500 |
| CFO | Donnelly Noel | Feb 26, 2025 | Sell | $2.57K | 1,527 |
| General Counsel | DeLena Mary Beth | Feb 26, 2025 | Sell | $2.41K | 1,432 |
| Chief Medical Officer | Mellion Michelle L | Jul 25, 2024 | Sell | $136.74K | 7,571 |
| Chief Medical Officer | Mellion Michelle L | Jul 24, 2024 | Sell | $3.62K | 201 |
| Chief Medical Officer | Mellion Michelle L | Jul 18, 2024 | Sell | $229.8K | 12,625 |
| Chief Medical Officer | Mellion Michelle L | Jul 16, 2024 | Sell | $106.25K | 5,901 |
| Chief Medical Officer | Mellion Michelle L | Jul 12, 2024 | Sell | $59.33K | 3,288 |
| Chief Medical Officer | Mellion Michelle L | Jul 2, 2024 | Sell | $668.59 | 37 |
| Chief Medical Officer | Mellion Michelle L | Jul 1, 2024 | Sell | $15.76K | 875 |
| Chief Medical Officer | Mellion Michelle L | Jun 24, 2024 | Sell | $168.43K | 9,260 |
| Chief Medical Officer | Mellion Michelle L | Jun 12, 2024 | Sell | $19.61K | 1,086 |
| Chief Medical Officer | Mellion Michelle L | Jun 11, 2024 | Sell | $9.02K | 500 |
| SVP, Clinical Development | Mellion Michelle L | Jun 6, 2024 | Sell | $25.4K | 1,411 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.