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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | Morrison Jodie Pope | Aug 25, 2026 | Sell | $163.03K | 9,845 |
| Chief Scientific Officer | Violette Shelia M. | Aug 25, 2026 | Sell | $46.33K | 2,798 |
| President | Kalowski Lee | Aug 25, 2026 | Sell | $65.78K | 3,972 |
| Director | ORBIMED ADVISORS LLC | May 28, 2026 | Buy | $10M | 1,250,000 |
| Director | Xu Diyong | May 28, 2026 | Buy | $10M | 1,250,000 |
| Director | ORBIMED ADVISORS LLC | May 28, 2026 | Buy | $5M | 625,000 |
| Director | Xu Diyong | May 28, 2026 | Buy | $5M | 625,000 |
| Chief Scientific Officer | Violette Shelia M. | Feb 25, 2026 | Sell | $12.71K | 2,815 |
| CEO | Morrison Jodie Pope | Feb 25, 2026 | Sell | $44.67K | 9,896 |
| President | Kalowski Lee | Feb 25, 2026 | Sell | $18.04K | 3,995 |
| President | Kalowski Lee | Dec 2, 2025 | Sell | $31.4K | 9,072 |
| CEO | Morrison Jodie Pope | Dec 2, 2025 | Sell | $77.87K | 22,506 |
| President | Kalowski Lee | Aug 26, 2025 | Sell | $7.64K | 4,240 |
| CEO | Morrison Jodie Pope | Aug 26, 2025 | Sell | $18.9K | 10,494 |
| Chief Scientific Officer | Violette Shelia M. | Aug 26, 2025 | Sell | $5.38K | 2,990 |
| See Remarks | Michaud Charles Jr | Mar 25, 2024 | Sell | $1.82K | 75 |
| See Remarks | Alloway Paul | Mar 25, 2024 | Sell | $6.49K | 268 |
| Director | TZIANABOS ARTHUR | Mar 25, 2024 | Sell | $6.41K | 265 |
| Director | TZIANABOS ARTHUR | Jan 9, 2024 | Sell | $7.45K | 13,037 |
| See Remarks | Alloway Paul | Jan 3, 2024 | Sell | $4.12K | 7,280 |
| See Remarks | Michaud Charles Jr | Jan 3, 2024 | Sell | $975.27 | 1,708 |
| Director | Seymour Albert | Sep 6, 2023 | Sell | $1.67K | 1,448 |
| Chief Medical Officer | Jordan Julie | Aug 3, 2023 | Sell | $606.04 | 436 |
| Chief Medical Officer | Jordan Julie | Aug 3, 2023 | Sell | $151.51 | 109 |
| Chief Medical Officer | Jordan Julie | Aug 3, 2023 | Sell | $1.82K | 1,308 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.