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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| SVP, Chief Accounting Officer | Huizenga Theodore Alan | Sep 15, 2026 | Sell | $17.41K | 1,283 |
| SVP, Chief Accounting Officer | Huizenga Theodore Alan | Sep 3, 2026 | Sell | $2.25K | 161 |
| EVP and Chief Legal Officer | Parschauer Karah Herdman | Aug 3, 2026 | Sell | $47.35K | 1,900 |
| CFO | Horn Howard | Aug 3, 2026 | Sell | $117.02K | 4,696 |
| CFO | Horn Howard | Jul 1, 2026 | Sell | $155.64K | 4,698 |
| EVP and Chief Legal Officer | Parschauer Karah Herdman | Jun 15, 2026 | Sell | $46.75K | 1,899 |
| Director | Sanders Corazon (Corsee) D. | Jun 15, 2026 | Sell | $50.1K | 2,000 |
| CFO | Horn Howard | Jun 1, 2026 | Sell | $110.6K | 4,653 |
| Director | SULIMAN SHEHNAAZ | May 18, 2026 | Sell | $144.19K | 5,740 |
| EVP and Chief Medical Officer | Crombez Eric | May 5, 2026 | Sell | $8.59K | 344 |
| CFO | Horn Howard | May 1, 2026 | Sell | $116.61K | 4,683 |
| CFO | Horn Howard | Apr 1, 2026 | Sell | $98.2K | 4,683 |
| EVP and Chief Legal Officer | Parschauer Karah Herdman | Mar 10, 2026 | Sell | $79.53K | 3,508 |
| EVP and Chief Legal Officer | Parschauer Karah Herdman | Mar 6, 2026 | Sell | $128.79K | 6,018 |
| CFO | Horn Howard | Mar 3, 2026 | Sell | $36.62K | 1,635 |
| EVP and Chief Legal Officer | Parschauer Karah Herdman | Mar 2, 2026 | Sell | $185.48K | 8,135 |
| SVP, Chief Accounting Officer | Huizenga Theodore Alan | Mar 2, 2026 | Sell | $37.21K | 1,632 |
| CEO | KAKKIS EMIL D | Mar 2, 2026 | Sell | $1.24M | 54,404 |
| EVP and Chief Medical Officer | Crombez Eric | Mar 2, 2026 | Sell | $160.26K | 7,029 |
| EVP & Chief Commercial Officer | Harris Erik | Mar 2, 2026 | Sell | $240.29K | 10,539 |
| CFO | Horn Howard | Mar 2, 2026 | Sell | $120.61K | 5,290 |
| See Remarks | Pinion John Richard | Mar 2, 2026 | Sell | $228.66K | 10,029 |
| CFO | Horn Howard | Mar 2, 2026 | Sell | $70.3K | 3,119 |
| CFO | Horn Howard | Feb 2, 2026 | Sell | $72.12K | 3,061 |
| CFO | Horn Howard | Jan 2, 2026 | Sell | $71.95K | 3,150 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.