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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CFO | Hill Emily Luisa | Aug 17, 2026 | Sell | $132.18K | 9,256 |
| Director | BAKER BROS. ADVISORS LP | Aug 11, 2026 | Buy | $1.52M | 126,394 |
| Director | BAKER BROS. ADVISORS LP | Aug 11, 2026 | Buy | $31.48M | 2,609,946 |
| Chief Medical Officer | Xynos Konstantinos | Aug 10, 2026 | Sell | $148.47K | 11,447 |
| Chief Accounting Officer | Schwendenman Andrew | Aug 10, 2026 | Sell | $98.99K | 7,632 |
| CFO | Hill Emily Luisa | Aug 10, 2026 | Sell | $148.48K | 11,448 |
| CEO | Patel Sushil | Aug 10, 2026 | Sell | $510.25K | 39,341 |
| Chief Commercial Officer | Sarchi Christopher | Jun 1, 2026 | Sell | $110.88K | 12,000 |
| CFO | Hill Emily Luisa | May 18, 2026 | Sell | $39.68K | 7,812 |
| CEO | Patel Sushil | May 18, 2026 | Sell | $189.61K | 37,324 |
| Chief Commercial Officer | Sarchi Christopher | May 18, 2026 | Sell | $43.82K | 8,626 |
| Director | Astley-Sparke Philip | May 18, 2026 | Sell | $89.7K | 17,657 |
| Chief Accounting Officer | Schwendenman Andrew | May 18, 2026 | Sell | $40.1K | 7,894 |
| Chief Medical Officer | Xynos Konstantinos | May 18, 2026 | Sell | $71.24K | 14,023 |
| Chief Commercial Officer | Sarchi Christopher | Apr 2, 2026 | Sell | $52.07K | 6,500 |
| Director | Dhingra Kapil | Dec 9, 2025 | Sell | $32.96K | 3,169 |
| CEO | Patel Sushil | Dec 2, 2025 | Sell | $111.3K | 10,000 |
| Chief Commercial Officer | Sarchi Christopher | Nov 17, 2025 | Sell | $47.39K | 5,208 |
| Chief Medical Officer | Xynos Konstantinos | Nov 17, 2025 | Sell | $65.96K | 7,248 |
| CFO | Hill Emily Luisa | Aug 15, 2025 | Sell | $49.16K | 9,154 |
| Chief Accounting Officer | Schwendenman Andrew | May 20, 2025 | Sell | $26.46K | 3,287 |
| Chief Commercial Officer | Sarchi Christopher | May 20, 2025 | Sell | $30.18K | 3,749 |
| CEO | Patel Sushil | May 20, 2025 | Sell | $202.35K | 25,105 |
| CFO | Hill Emily Luisa | May 20, 2025 | Sell | $20.41K | 2,535 |
| Chief Medical Officer | Xynos Konstantinos | May 20, 2025 | Sell | $64.09K | 7,952 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.