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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | Boyce Sarah | Jan 21, 2026 | Sell | $463.25K | 6,394 |
| CFO | MacLean Michael F | Jan 21, 2026 | Sell | $130.92K | 1,807 |
| Chief Human Resources Officer | McCarthy Teresa | Jan 21, 2026 | Sell | $106.94K | 1,476 |
| Chief Scientific Officer | Flanagan W. Michael | Jan 21, 2026 | Sell | $288.06K | 3,976 |
| Director | LEVIN ARTHUR A | Jan 21, 2026 | Sell | $127.37K | 1,758 |
| Chief Medical Officer | Hughes Steven George | Jan 21, 2026 | Sell | $146.13K | 2,017 |
| CEO | Boyce Sarah | Jan 21, 2026 | Sell | $579.09K | 7,993 |
| Chief Scientific Officer | Flanagan W. Michael | Jan 21, 2026 | Sell | $185.33K | 2,558 |
| Chief Medical Officer | Hughes Steven George | Jan 21, 2026 | Sell | $208.51K | 2,878 |
| CFO | MacLean Michael F | Jan 21, 2026 | Sell | $198.15K | 2,735 |
| Chief Human Resources Officer | McCarthy Teresa | Jan 21, 2026 | Sell | $105.27K | 1,453 |
| CFO | MacLean Michael F | Jan 7, 2026 | Sell | $142.58K | 1,974 |
| Chief Legal Officer | Moriarty John B | Jan 7, 2026 | Sell | $171.47K | 2,374 |
| Chief Scientific Officer | Flanagan W. Michael | Jan 7, 2026 | Sell | $171.4K | 2,373 |
| Chief Technical Officer | Calderaro Charles III | Jan 7, 2026 | Sell | $269.2K | 3,727 |
| Chief Medical Officer | Hughes Steven George | Jan 7, 2026 | Sell | $171.4K | 2,373 |
| CEO | Boyce Sarah | Jan 7, 2026 | Sell | $619.44K | 8,576 |
| Chief Human Resources Officer | McCarthy Teresa | Jan 7, 2026 | Sell | $141.93K | 1,965 |
| Chief Medical Officer | Hughes Steven George | Oct 22, 2025 | Sell | $105.01K | 2,209 |
| Chief Human Resources Officer | McCarthy Teresa | Oct 15, 2025 | Sell | $1M | 20,000 |
| Chief Commercial Officer | Mosbrooker Eric | Oct 3, 2025 | Sell | $297.77K | 6,562 |
| Chief Medical Officer | Hughes Steven George | Sep 22, 2025 | Sell | $89.6K | 2,208 |
| Chief Human Resources Officer | McCarthy Teresa | Sep 15, 2025 | Sell | $621.14K | 15,000 |
| Chief Medical Officer | Hughes Steven George | Sep 15, 2025 | Sell | $70.02K | 1,542 |
| Chief Scientific Officer | Flanagan W. Michael | Sep 11, 2025 | Sell | $778.7K | 20,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
