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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | Kemble George | Aug 11, 2026 | Sell | $201.15K | 20,206 |
| Director | Kemble George | Jul 20, 2026 | Sell | $140.53K | 18,844 |
| CEO | Happel David | Jul 20, 2026 | Sell | $497.07K | 64,051 |
| Chief Legal & Admin. Officer | Rozek Elizabeth | Jul 20, 2026 | Sell | $81.83K | 10,545 |
| Chief Medical Officer | Martins Eduardo Bruno | Feb 10, 2026 | Sell | $19.51K | 3,640 |
| Chief Legal & Admin. Officer | Rozek Elizabeth | Feb 10, 2026 | Sell | $14.05K | 2,622 |
| CEO | Happel David | Feb 10, 2026 | Sell | $64.86K | 12,101 |
| CFO | Chauche Thierry | Feb 10, 2026 | Sell | $7.03K | 1,312 |
| Chairman | Kemble George | Nov 20, 2025 | Sell | $289.98K | 37,688 |
| General Counsel and CCO | Rozek Elizabeth | Jul 21, 2025 | Sell | $98.47K | 10,780 |
| Chief Medical Officer | Martins Eduardo Bruno | Jul 21, 2025 | Sell | $75.61K | 8,277 |
| CEO | Happel David | Jul 21, 2025 | Sell | $598.12K | 65,478 |
| Chairman | Kemble George | Jul 23, 2024 | Sell | $74.83K | 23,625 |
| Chief Medical Officer | Martins Eduardo Bruno | Jul 19, 2024 | Sell | $25.91K | 8,357 |
| Chairman | Kemble George | Jul 19, 2024 | Sell | $43.6K | 14,062 |
| General Counsel and CCO | Rozek Elizabeth | Jul 19, 2024 | Sell | $33.83K | 10,914 |
| CEO | Happel David | Mar 26, 2024 | Buy | $63.73K | 12,100 |
| CEO | Happel David | Dec 7, 2023 | Buy | $6.56K | 1,600 |
| CEO | Happel David | Nov 16, 2023 | Buy | $1.39K | 590 |
| Director | SEIDENBERG BETH C | Jul 18, 2023 | Buy | $750K | 46,875 |
| 10% Owner | NEW ENTERPRISE ASSOCIATES 13 LP | Jul 18, 2023 | Sell | $10.59K | 662 |
| 10% Owner | NEW ENTERPRISE ASSOCIATES 13 LP | Jul 18, 2023 | Buy | $480K | 30,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.