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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | Thompson Peter A. | Jul 7, 2026 | Sell | $3.85M | 85,918 |
| Director | ORBIMED ADVISORS LLC | Jul 7, 2026 | Sell | $3.85M | 85,918 |
| Chief Legal Officer | Fitzpatrick Jennifer | Jul 6, 2026 | Sell | $446.86K | 10,250 |
| Director | ORBIMED ADVISORS LLC | Jun 30, 2026 | Sell | $5.27M | 115,844 |
| Director | Thompson Peter A. | Jun 30, 2026 | Sell | $5.27M | 115,844 |
| Director | ORBIMED ADVISORS LLC | May 27, 2026 | Sell | $4.49K | 101 |
| Director | Thompson Peter A. | May 27, 2026 | Sell | $4.49K | 101 |
| Director | Thompson Peter A. | May 11, 2026 | Sell | $8.53M | 184,639 |
| Director | ORBIMED ADVISORS LLC | May 11, 2026 | Sell | $8.53M | 184,639 |
| Director | ORBIMED ADVISORS LLC | May 8, 2026 | Sell | $2.66M | 59,767 |
| Director | Thompson Peter A. | May 8, 2026 | Sell | $2.66M | 59,767 |
| Director | ORBIMED ADVISORS LLC | May 7, 2026 | Sell | $2.17M | 48,546 |
| Director | Thompson Peter A. | May 7, 2026 | Sell | $2.17M | 48,546 |
| Director | ORBIMED ADVISORS LLC | Apr 18, 2026 | Sell | $131.24K | 2,948 |
| Director | Thompson Peter A. | Apr 18, 2026 | Sell | $131.24K | 2,948 |
| Director | Thompson Peter A. | Apr 17, 2026 | Sell | $2.34M | 52,397 |
| Director | ORBIMED ADVISORS LLC | Apr 17, 2026 | Sell | $2.34M | 52,397 |
| Director | Thompson Peter A. | Apr 16, 2026 | Sell | $10.29M | 226,906 |
| Director | ORBIMED ADVISORS LLC | Apr 16, 2026 | Sell | $10.29M | 226,906 |
| Director | Thompson Peter A. | Apr 15, 2026 | Sell | $10.53M | 235,863 |
| Director | ORBIMED ADVISORS LLC | Apr 15, 2026 | Sell | $10.53M | 235,863 |
| Director | Thompson Peter A. | Apr 14, 2026 | Sell | $2.13M | 47,814 |
| Director | ORBIMED ADVISORS LLC | Apr 14, 2026 | Sell | $2.13M | 47,814 |
| Chief Legal Officer | Fitzpatrick Jennifer | Mar 5, 2026 | Sell | $347.02K | 10,250 |
| Director | Thompson Peter A. | Feb 3, 2026 | Sell | $1.3M | 29,063 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.