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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| 10% Owner | 5AM Partners VII, LLC | Aug 20, 2026 | Sell | $370.88 | 1,159 |
| Director | Schwab Andrew J. | Aug 20, 2026 | Sell | $370.88 | 1,159 |
| Director | Schwab Andrew J. | Aug 20, 2026 | Sell | $14.72 | 46 |
| 10% Owner | 5AM Partners VII, LLC | Aug 20, 2026 | Sell | $14.72 | 46 |
| 10% Owner | 5AM Partners VII, LLC | Aug 20, 2026 | Sell | $2.08K | 6,495 |
| Director | Schwab Andrew J. | Aug 20, 2026 | Sell | $2.08K | 6,495 |
| Director | Schwab Andrew J. | Aug 19, 2026 | Sell | $3.59K | 10,255 |
| 10% Owner | 5AM Partners VII, LLC | Aug 19, 2026 | Sell | $3.59K | 10,255 |
| 10% Owner | 5AM Partners VII, LLC | Aug 19, 2026 | Sell | $143.15 | 409 |
| Director | Schwab Andrew J. | Aug 19, 2026 | Sell | $143.15 | 409 |
| Director | Schwab Andrew J. | Aug 19, 2026 | Sell | $20.12K | 57,476 |
| 10% Owner | 5AM Partners VII, LLC | Aug 19, 2026 | Sell | $20.12K | 57,476 |
| 10% Owner | 5AM Partners VII, LLC | Aug 18, 2026 | Sell | $17.13K | 45,090 |
| Director | Schwab Andrew J. | Aug 18, 2026 | Sell | $17.13K | 45,090 |
| Director | Schwab Andrew J. | Aug 18, 2026 | Sell | $695.4 | 1,830 |
| 10% Owner | 5AM Partners VII, LLC | Aug 18, 2026 | Sell | $695.4 | 1,830 |
| 10% Owner | 5AM Partners VII, LLC | Aug 18, 2026 | Sell | $96.17K | 253,080 |
| Director | Schwab Andrew J. | Aug 18, 2026 | Sell | $96.17K | 253,080 |
| Director | Schwab Andrew J. | Aug 22, 2025 | Sell | $560.81K | 163,979 |
| 10% Owner | 5AM Partners VII, LLC | Aug 22, 2025 | Sell | $560.81K | 163,979 |
| Director | Schwab Andrew J. | Aug 22, 2025 | Sell | $22.13K | 6,470 |
| 10% Owner | 5AM Partners VII, LLC | Aug 22, 2025 | Sell | $22.13K | 6,470 |
| Director | Schwab Andrew J. | Aug 21, 2025 | Sell | $209.35K | 58,642 |
| 10% Owner | 5AM Partners VII, LLC | Aug 21, 2025 | Sell | $209.35K | 58,642 |
| Director | Schwab Andrew J. | Aug 21, 2025 | Sell | $8.26K | 2,314 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.