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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | New Enterprise Associates 14, L.P. | Jul 27, 2026 | Buy | - | 2,640,845 |
| See Remarks below | Dooley Mary Beth | Oct 29, 2025 | Sell | $284.17 | 157 |
| See Remarks below | Dooley Mary Beth | Apr 2, 2025 | Sell | $172.8 | 144 |
| See Remarks below | Dooley Mary Beth | Feb 3, 2025 | Sell | $2.8K | 2,107 |
| Head of Finance | Dooley Mary Beth | Oct 29, 2024 | Sell | $110.6 | 79 |
| Chief Operating Officer | Awad Antoine | Apr 2, 2024 | Sell | $643.56 | 372 |
| Head of Finance | Dooley Mary Beth | Apr 2, 2024 | Sell | $325.24 | 188 |
| CFO | JENSEN MICHAEL VANGSTED | Apr 3, 2023 | Sell | $1.47K | 2,553 |
| Director | Brennan Aoife | Apr 3, 2023 | Sell | $10.96K | 19,042 |
| Chief Operating Officer | Awad Antoine | Apr 3, 2023 | Sell | $3.71K | 6,438 |
| CFO | JENSEN MICHAEL VANGSTED | May 24, 2022 | Buy | $10.64K | 9,500 |
| Chief Operating Officer | Awad Antoine | Apr 4, 2022 | Sell | $6.48K | 2,650 |
| Director | Brennan Aoife | Apr 4, 2022 | Sell | $21.75K | 8,894 |
| Director | Shea Richard P | Dec 13, 2019 | Buy | $20.55K | 7,500 |
| Chief Scientific Officer | Miller Paul Francis | Feb 13, 2019 | Sell | $57.03K | 5,849 |
| Chief Scientific Officer | Miller Paul Francis | Feb 12, 2019 | Sell | $30.72K | 3,151 |
| Chief Scientific Officer | Miller Paul Francis | Oct 18, 2018 | Sell | $29.3K | 3,000 |
| Chief Scientific Officer | Miller Paul Francis | Sep 18, 2018 | Sell | $39.16K | 3,000 |
| Chief Scientific Officer | Miller Paul Francis | Sep 5, 2018 | Sell | $37.64K | 3,000 |
| Chief Scientific Officer | Miller Paul Francis | Aug 30, 2018 | Sell | $13.09K | 1,342 |
| Chief Scientific Officer | Miller Paul Francis | Aug 29, 2018 | Sell | $16.2K | 1,658 |
| Chief Scientific Officer | Miller Paul Francis | Jul 18, 2018 | Sell | $33.02K | 3,000 |
| Chief Scientific Officer | Miller Paul Francis | Jun 20, 2018 | Sell | $10.33K | 1,054 |
| Chief Scientific Officer | Miller Paul Francis | Jun 20, 2018 | Sell | $9.75K | 1,000 |
| Chief Scientific Officer | Miller Paul Francis | Jun 19, 2018 | Sell | $9.22K | 946 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.