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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| CEO | Ali Faraz | Aug 17, 2026 | Sell | $4.14K | 5,837 |
| CEO | Ali Faraz | Aug 17, 2026 | Sell | $2.82K | 3,969 |
| CEO | Ali Faraz | Aug 17, 2026 | Sell | $3.56K | 5,020 |
| CEO | Ali Faraz | Aug 17, 2026 | Sell | $5.26K | 7,406 |
| CEO | Ali Faraz | May 18, 2026 | Sell | $2.69K | 3,390 |
| SVP, Finance | Higa Tomohiro | May 18, 2026 | Sell | $1.18K | 1,485 |
| Chief Medical Officer | Tingley Whittemore | May 18, 2026 | Sell | $2.48K | 3,121 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 25, 2026 | Sell | $927.56K | 1,649,281 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 25, 2026 | Sell | $1.05M | 1,862,545 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 24, 2026 | Sell | $190.27K | 309,228 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 24, 2026 | Sell | $214.87K | 349,212 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 23, 2026 | Sell | $85.82K | 143,709 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 23, 2026 | Sell | $96.92K | 162,291 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 20, 2026 | Sell | $151.24K | 245,965 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 20, 2026 | Sell | $170.8K | 277,769 |
| Chief Medical Officer | Tingley Whittemore | Feb 17, 2026 | Sell | $1.06K | 1,642 |
| CEO | Ali Faraz | Feb 17, 2026 | Sell | $3.76K | 5,851 |
| SVP, Finance | Higa Tomohiro | Feb 17, 2026 | Sell | $393.12 | 611 |
| CEO | Ali Faraz | Feb 17, 2026 | Sell | $2.56K | 3,979 |
| SVP, Finance | Higa Tomohiro | Feb 17, 2026 | Sell | $537.88 | 836 |
| Chief Medical Officer | Tingley Whittemore | Feb 17, 2026 | Sell | $1.06K | 1,642 |
| CEO | Ali Faraz | Feb 17, 2026 | Sell | $3.24K | 5,032 |
| Chief Medical Officer | Tingley Whittemore | Feb 17, 2026 | Sell | $1.21K | 1,876 |
| SVP, Finance | Higa Tomohiro | Feb 17, 2026 | Sell | $1.3K | 2,022 |
| 10% Owner | COLUMN GROUP III GP, LP | Feb 11, 2026 | Sell | $1.3M | 1,905,115 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.