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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | Napolitano Janet | Jun 1, 2026 | Sell | $30.24K | 3,200 |
| SVP, Chief Accounting Officer | Sabatini Brent | Jun 1, 2026 | Sell | $3.58K | 379 |
| Director | SATO VICKI L | May 1, 2026 | Sell | $221.03K | 22,000 |
| CEO | De Backer Marianne | Apr 6, 2026 | Sell | $664.35K | 72,559 |
| Director | SATO VICKI L | Apr 1, 2026 | Sell | $199.62K | 22,000 |
| SVP, Chief Accounting Officer | Sabatini Brent | Mar 23, 2026 | Sell | $70.32K | 7,711 |
| Director | SATO VICKI L | Mar 2, 2026 | Sell | $207.19K | 21,800 |
| Director | SATO VICKI L | Mar 2, 2026 | Sell | $2K | 200 |
| EVP and Chief Medical Officer | Eisner Mark | Feb 25, 2026 | Sell | $18.55K | 1,889 |
| EVP, General Counsel, Corp Sec | de Verneuil Vanina | Feb 25, 2026 | Sell | $134.53K | 13,700 |
| CEO | De Backer Marianne | Feb 24, 2026 | Sell | $140.72K | 14,762 |
| CFO | O'Byrne Jason | Feb 24, 2026 | Sell | $15.58K | 1,634 |
| EVP and Chief Medical Officer | Eisner Mark | Feb 24, 2026 | Sell | $15.4K | 1,616 |
| EVP, General Counsel, Corp Sec | de Verneuil Vanina | Feb 24, 2026 | Sell | $29.71K | 3,117 |
| SVP, Chief Accounting Officer | Sabatini Brent | Feb 24, 2026 | Sell | $13.63K | 1,430 |
| Director | SATO VICKI L | Feb 24, 2026 | Sell | $411.31K | 42,177 |
| Director | SATO VICKI L | Feb 24, 2026 | Sell | $2.05K | 200 |
| CEO | De Backer Marianne | Feb 23, 2026 | Sell | $141.89K | 19,039 |
| SVP, Chief Accounting Officer | Sabatini Brent | Feb 23, 2026 | Sell | $13.63K | 1,829 |
| EVP, General Counsel, Corp Sec | de Verneuil Vanina | Feb 23, 2026 | Sell | $33.13K | 4,445 |
| EVP and Chief Medical Officer | Eisner Mark | Feb 23, 2026 | Sell | $15.57K | 2,089 |
| CFO | O'Byrne Jason | Feb 23, 2026 | Sell | $15.57K | 2,089 |
| SVP, Chief Accounting Officer | Sabatini Brent | Feb 13, 2026 | Sell | $11.92K | 1,530 |
| Director | SATO VICKI L | Feb 2, 2026 | Sell | $169.67K | 22,000 |
| Director | SATO VICKI L | Jan 2, 2026 | Sell | $130.38K | 22,000 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
