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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| Director | Bailey Gregory | Aug 19, 2022 | Buy | $5.63M | 38,000 |
| VP, Chief Accounting Officer | Clark George C. | May 10, 2022 | Sell | $594.3K | 4,200 |
| VP, Chief Accounting Officer | Clark George C. | Jan 19, 2022 | Sell | $367.31K | 3,196 |
| VP, Chief Accounting Officer | Clark George C. | Jan 19, 2022 | Sell | $250.48K | 2,159 |
| VP, Chief Accounting Officer | Clark George C. | Jan 19, 2022 | Sell | $59.02K | 500 |
| VP, Chief Accounting Officer | Clark George C. | Jan 19, 2022 | Sell | $420.18K | 3,520 |
| VP, Chief Accounting Officer | Clark George C. | Dec 20, 2021 | Sell | $237.15K | 1,915 |
| Director | GREGORY JULIA P | Dec 20, 2021 | Sell | $1.5M | 12,000 |
| Chief Medical Officer | Stock Elyse | Dec 15, 2021 | Sell | $2.14M | 20,330 |
| Chief Medical Officer | Stock Elyse | Dec 15, 2021 | Sell | $168.7K | 1,589 |
| Chief Medical Officer | Stock Elyse | Dec 14, 2021 | Sell | $728.76K | 6,939 |
| CFO | Engelhart James | Dec 10, 2021 | Sell | $1.03M | 10,131 |
| CFO | Engelhart James | Dec 10, 2021 | Sell | $2.41M | 23,487 |
| CFO | Engelhart James | Dec 10, 2021 | Sell | $143.52K | 1,382 |
| Director | Doogan Declan | Nov 29, 2021 | Sell | $1.46M | 13,026 |
| Director | Doogan Declan | Nov 29, 2021 | Sell | $1.3M | 11,499 |
| Director | Doogan Declan | Nov 16, 2021 | Sell | $1.44M | 12,437 |
| Director | Doogan Declan | Nov 16, 2021 | Sell | $2.13M | 18,230 |
| Director | Doogan Declan | Nov 16, 2021 | Sell | $833.71K | 7,073 |
| Director | CHILDS JOHN W | Nov 10, 2021 | Buy | $477.48K | 3,890 |
| Director | CHILDS JOHN W | Nov 10, 2021 | Buy | $136.86K | 1,110 |
| Director | CHILDS JOHN W | Mar 17, 2021 | Buy | $999.93K | 13,157 |
| Director | CHILDS JOHN W | Mar 2, 2021 | Buy | $851.37K | 10,000 |
| Director | CHILDS JOHN W | Nov 23, 2020 | Buy | $447.74K | 5,000 |
| CCO-Migraine & Common Disease | JONES WILLIAM A JR | Nov 2, 2020 | Sell | $1.88M | 24,690 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.
