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| Role | Insider | Date | Transaction | Value | Shares |
|---|---|---|---|---|---|
| 10% Owner | FROST PHILLIP MD ET AL | Dec 21, 2018 | Buy | $500K | 7,142,857 |
| CEO | HSIAO JANE PH D | Dec 21, 2018 | Buy | $100K | 1,428,571 |
| 10% Owner | FROST PHILLIP MD ET AL | Dec 21, 2018 | Buy | $1.83M | 26,212,468 |
| CEO | HSIAO JANE PH D | Dec 21, 2018 | Buy | $344.65K | 4,923,503 |
| CEO | HSIAO JANE PH D | Dec 21, 2018 | Buy | $1.46M | 20,883,660 |
Open-market purchases and sales reported on SEC form 4 over the last 10years. Awards, option exercises, gifts and other non-market form 4 activity are excluded. Chart markers group a day's filings by direction; the table lists each filing.